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Bacterial entropathogens and antimicrobial susceptibility in children with acute diarrhea in Babol, Iran
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| Mohammad Reza Esmaeili Dooki , Ramazan Rajabnia, Rahim Barari Sawadkohi, Zahra Mosaiebnia Gatabi, Mohammad Poornasrollah , Mohaddeseh Mirzapour |
| MD Non-Communicable pediatric Diseases Research Center, Babol University of Medical Sciences, Babol, Iran , esmaeilidooki@yahoo.com |
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Abstract: (4360 Views) |
| Abstract
Background: Infectious diarrhea is one of common cause of children diarrhea causing mortality and morbidity worldwide. This study was performed to identify the common bacteria and their antimicrobial susceptibility in children with diarrhea.
Methods: Children under 14 years old with acute diarrhea who referred to Amirkola Children’s Hospital, Mazandaran, North of Iran, were enrolled during the summer and fall of 2009. From each patient, two fecal specimens were collected. Samples were cultured and bacterial isolation was done by conventional methods. Antimicrobial susceptibility was identified by disk diffusion and micro dilution methods.
Results: One hundred-seventy two patients with the mean age of 41.8±37.6 months were evaluated. The bacteria were isolated in 48 (27.9%) cases. The most common isolated bacteria was E.coli and then shigella in both bloody and nonbloody diarrheal patients. There was a significant difference between bacteria positive specimens and WBC in stool smear (p=0.003). All isolated shigella were susceptible to Ceftizoxime and ciprofloxacin and were resistant to Cefixime. Resistant to Nalidixic acid was seen in 14% of them.
Conclusion: The results show that E.coli was the most frequently isolated pathogen in children with bloody and nonbloody diarrhea. Ceftizoxime is a good antibiotic for shigellosis in children in our area but Cefixime is not appropriate. |
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| Keywords: Diarrhea, Drug, Resistance, Antibiotic, Dysentery |
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Full-Text [PDF 143 kb]
(652 Downloads)
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Type of Study: Original Article |
Subject:
Infectious Diseases
Received: 2013/12/18 | Accepted: 2013/12/18 | Published: 2013/12/18
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