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International Journal of Molecular and Cellular Medicine، جلد ۳، شماره ۲، صفحات ۱۲۶-۱۲۹
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژههای فارسی مقاله |
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| عنوان انگلیسی |
Screening of Different Organs of Rats for HCA2 Receptor mRNA |
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| چکیده انگلیسی مقاله |
Interest in hydroxy - carboxylic acid 2 (HCA2) receptor has been raised since it is the target of antidyslipidemic drug nicotinic acid. The present study aimed to evaluate the presence of mRNA of this receptor in different organs of laboratory rat. Twenty two different organs of rats including mesenteric fat, epididymis (head, body and tail), testis, ovary, xiphoid process, liver, adrenal gland, femoral head, proximal epiphyseal and metaphyseal bone marrow of femur, esophagus, glandular stomach, forestomach, intestines, colons, heart, spleen, kidney, trachea, lung, skeletal muscle (quadriceps), cerebrum and cerebellum were removed and examined for HCA2 mRNA by RT- PCR method. The mRNA for HCA2 receptor was detected in all tissues analyzed. In conclusion, different organs of rat express HCA2 receptor mRNA which makes it a proper animal model for future studies on the physiological and pharmacological roles of this receptor in vivo. |
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| کلیدواژههای انگلیسی مقاله |
HCA2 receptor mRNA, rat, RT-PCR |
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| نویسندگان مقاله |
طهورا شمالی | tahoora shomali division of pharmacology and toxicology, department of basic sciences, school of veterinary medicine, shiraz university, shiraz, iran.
سازمان اصلی تایید شده: دانشگاه شیراز (Shiraz university)
نجمه مصلح | najmeh mosleh avian disease research center, school of veterinary medicine, shiraz university, shiraz, iran.
سازمان اصلی تایید شده: دانشگاه شیراز (Shiraz university)
محمد کمال پور | mohammad kamalpour division of pharmacology and toxicology, department of basic sciences, school of veterinary medicine, shiraz university, shiraz, iran.
سازمان اصلی تایید شده: دانشگاه شیراز (Shiraz university)
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| نشانی اینترنتی |
http://www.ijmcmed.org/browse.php?a_code=A-10-191-1&slc_lang=en&sid=en |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
7 |
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