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Caspian Journal of Internal Medicine، جلد ۱۳، شماره ۲، صفحات ۵-۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Recover burn ointment for managing acute radiodermatitis in patients with breast cancer: A double blind randomized controlled trial |
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| چکیده انگلیسی مقاله |
Background: Radiodermatitis is the most common complication of radiotherapy. There is no gold standard for managing the radiodermatitis. This study aimed to evaluate the effect of topical Recove® burn ointment; basically compounded of sesame oil, camphor, and zinc oxide; in preventing acute radiodermatitis. Methods: This double blind RCT (IRCT No.: 201204047136N2) was performed on 71 patients that referred for radiotherapy after mastectomy to Shahid Rajaee Hospital (Babolsar-Iran) during 2013-2017. Patients were allocated into 2 groups; 34 in control group and 37 in Recove® group. Patients applied the ointment 2 times a day, before every radiation therapy session for 5 weeks. The radiation oncologist assessed the severity of dermatitis weekly for 5 weeks and graded it from 0 to 4 according to the RTOG criteria. Results:Baseline characteristics including age, and BMI had no significant difference between groups. The Recover group patients experienced significantly less severe dermatitis compared to the controls (p< 0.001). None of the patients in Recove® group encountered more than grade 2 of RTOG criteria, however, in the control group, 4 (12.9%)patients experienced grade 3 of RTOG and 3 (9.7%)patients developed grade 4 of RTOG at the end of the 5th week. Conclusion: Our results indicate that Recove® ointment significantly reduces the severity of acute radiodermatitis. |
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| کلیدواژه‌های انگلیسی مقاله |
breast cancer, radiotherapy, radiodermatitis, Recove ointment, radiation therapy oncology group. |
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| نویسندگان مقاله |
| Dariush Moslemi
Babol University of Medical Sciences
| Nargeuss Abbaszade Marzbali
Babol University of Medical Sciences
| Ebrahim Zabihi
Babol University of Medical Sciences
| Nicolas Magne
Department of Radiotherapy, Lucien Neuwirth Cancer Institute, Saint-Priest en Jarez, France
| Alexis Vallard
Department of Radiotherapy, Lucien Neuwirth Cancer Institute, Saint-Priest en Jarez, France
| Mohammad Moslemi
Babol University of Medical Sciences
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| نشانی اینترنتی |
http://caspjim.com/browse.php?a_code=A-10-2034-1&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Oncology |
| نوع مقاله منتشر شده |
Original Article |
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