|
|
Caspian Journal of Internal Medicine، جلد ۱۳، شماره ۲، صفحات ۸-۰
|
|
|
| عنوان فارسی |
|
|
| چکیده فارسی مقاله |
|
|
| کلیدواژه‌های فارسی مقاله |
|
|
| عنوان انگلیسی |
Safety of Laparoscopic Splenectomy for Patients with Idiopathic Thrombocytopenic Purpura and Very Low Platelet Count |
|
| چکیده انگلیسی مقاله |
Background: Chronic idiopathic thrombocytopenic purpura (ITP), is an autoimmune disease associated with a reduction in circulating blood platelets under 150x109/L which persists longer than 6 months without any specific cause. With the current study, we aimed to evaluate the efficacy and safety of laparoscopic splenectomy in ITP patients with a very low platelet count and normal coagulation status. Methods: From April 2007 to January 2012, laparoscopic splenectomy was performed on 60 patients with chronic ITP who could not achieve a sustained recovery after steroid therapy. Results: Patients consisted of male/female ratio of 24 (40%):36 (60%) with the mean age of 53±15.1 years. All patients had normal coagulation state even with very low platelet count (below 5×103) before laparoscopic splenectomy. The mean operative time was 140.00±15.00 minutes. Blood transfusion was required in 10 (16.7%) and 8 (13.3%) patients before and after the operation, respectively. Preoperative transfusion of PRBC was not statistically significant between groups (P=0.265). Bleeding complications during within or after surgery was rare (5.0%). Convalescence was rapid and the mean hospital stay was 3.58±0.68 days (1-14 days) which shows that there was no significant difference in operative time and after operative hospitalization time among the three groups (P=0.070). The patients made a good uneventful recovery and were followed for at least one week who exhibited no postoperative problems. Conclusion: Laparoscopic splenectomy should be considered initially in the management of ITP. Also, very low platelet count should not be contraindicated for laparoscopic splenectomy in ITP patients and sometimes perioperative platelet transfusion may be unnecessary. |
|
| کلیدواژه‌های انگلیسی مقاله |
Laparoscopy, Splenectomy, Purpura, Thrombocytopenic, Idiopathic, Steroids |
|
| نویسندگان مقاله |
| Abbas Abdollahi
Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
| Seyed Maryam Naghibi
Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
| Hamed Shariat Razavi
Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
| Alireza Tavassoli
Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
| Azadeh Jabbari Nooghabi
Surgical Oncology Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
| Mehdi Jabbari Nooghabi
Department of Statistics, Faculty of Mathematical Sciences, Ferdowsi University of Medical Sciences, Mashhad, Iran
|
|
| نشانی اینترنتی |
http://caspjim.com/browse.php?a_code=A-10-128-3&slc_lang=en&sid=1 |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
|
| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Surgery |
| نوع مقاله منتشر شده |
Original Article |
|
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|