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Caspian Journal of Internal Medicine، جلد ۱۳، شماره ۲، صفحات ۱۰-۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژههای فارسی مقاله |
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| عنوان انگلیسی |
Clinical Laboratory Parameters in Different Stages, Zones, and Remission/Progression statuses of Retinopathy of Prematurity |
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| چکیده انگلیسی مقاله |
Background: Retinopathy of prematurity (ROP) is a vasoproliferative retinal disease in premature infants that causes lifetime visual impairment and blindness in the early ages. In this study, we investigated the differences in the values of clinical laboratory parameters between different ROP and its remission/progression statuses regarding stages and zones. Methods: This historical cohort study includes 828 infants divided into two groups after the first examination containing ROP infants and controls. The biochemical and hematological parameters of the two groups have been collected from the patient's history. Results: In infants with ROP, the hematopoiesis-related parameters, including the mean level of hemoglobin, total bilirubin, potassium, calcium were significantly less than controls (P =0.039, P =0.001, P =0.001, and P=0.046, respectively). The percentages of reticulocyte and the levels of BUN in ROP patients were significantly higher than in normal infants (P=0.015 and p < 0.001, respectively). Moreover, the levels of hemoglobin and BUN were significantly different in the different zones of ROP (P=0.017 and P=0.001, respectively). Also, higher hemoglobin levels, total bilirubin, and CRP were observed in the reduced stages of ROP (P=0.041, P=0.045, and P=0.039, respectively). Conclusion: Laboratory parameters are different in different stages, zones and remission/progression ROP infants. |
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| کلیدواژههای انگلیسی مقاله |
Retinopathy of prematurity, Prognosis, Laboratory parameters, Hematologic parameters, Biochemical parameters. |
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| نویسندگان مقاله |
| Seyed Ahmad Rasoulinejad Department of Ophthalmology, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran
| Faezeh Maroufi Department of Medical Laboratory Sciences, Faculty of Allied Medicine, Qazvin University of Medical Sciences, Qazvin, Iran
| Ahad Alizadeh Metabolic Diseases Research Center, Qazvin University of Medical Sciences, Qazvin, Iran
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| نشانی اینترنتی |
http://caspjim.com/browse.php?a_code=A-10-2197-2&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Ophtalmology |
| نوع مقاله منتشر شده |
Original Article |
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