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Caspian Journal of Internal Medicine، جلد ۱۳، شماره ۱، صفحات ۲۹-۳۷
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Hypoglycemia: Elucidating Its Circadian Propensity and Recovery Time Based on Clinical Parameters |
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| چکیده انگلیسی مقاله |
Background: Hypoglycemia is frequently associated with insulin therapy in diabetic patients; it leads to many short and long-term complications and even death if not addressed in time. This study was undertaken to observe the circadian propensity of hypoglycemia and its recovery time based on type 2 diabetes mellitus patients' clinical parameters. Methods: We included type 2 diabetes mellitus (DM) hospitalized patients with the exclusion of patients suffering from critical illness. Data were collected for a period of three months (September to November 2019). Results: A total of 120 patients were included, comprising 60% males and 40% females. Approximately 55% of patients had hypoglycemic episodes at around 12 am– 6 am. The most common comorbidity present in these patients was hypertension (43.3%, P=0.931). Anemia (OR-3.765, CI-1.350-5.500, P=0.011), retinopathy (OR 6.066, CI-2.031-8.113, P=0.001), and duration of DM (OR-6.266, CI-2.209-7.774, P=0.001) were significantly associated with the recovery time of hypoglycemia, around 50±14.14min in the elderly population of age 60-70. People with BMI 22.5- 27.5 Kg/m2 took around 45.66 ± 19.37 min to recover after treatment. Conclusion: Time taken to recover from hypoglycemic episodes vary with age and BMI. Associated comorbidities such as anemia, retinopathy, and DM duration had a significant bearing on the time taken to recover from hypoglycemia. Recovery time was directly proportional to BMI, a new finding that needs further molecular level evaluation. Circadian propensity of hypoglycemia in these patients have been identified in the early morning hours of the day. |
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| کلیدواژه‌های انگلیسی مقاله |
Anemia, Body mass index, Comorbidity, Diabetes Mellitus, Hypoglycemia, hypoglycemic episode, Insulin, Retinopathy |
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| نویسندگان مقاله |
| Ravi Kant
Department of Medicine, All India Institute of Medical Sciences, Rishikesh, India
| Poonam Yadav
Center of Excellence in Nursing Education and Research, All India Institute of Medical Sciences, Rishikesh, India
| Madhuri Pratti
Department of Medicine, All India Institute of Medical Sciences, Rishikesh, India
| Shruti Barnwal
Department of Dermatology, Govt. Doon Medical College, Dehradun, India
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| نشانی اینترنتی |
http://caspjim.com/browse.php?a_code=A-10-2131-1&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Endocrinology |
| نوع مقاله منتشر شده |
Original Article |
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