| چکیده انگلیسی مقاله |
Background: Systemic lupus erythematous (SLE) and rheumatoid arthritis (RA) are autoimmune diseases in which the antigen-antibody system plays an important role. As blood group and Rh are determined by the presence or absence of antigens on the surface of red blood cells (RBCs), we aimed to determine the distribution of ABO and Rh blood groups in SLE and RA patients and its association with disease manifestations. Methods: This short communication is based on a study that was conducted on 434 SLE and 828 RA patients. We evaluated the distribution of ABO and Rh blood groups in RA and SLE patients. Results: This study projected that in lupus patients, Coombs-positive autoimmune hemolytic anemia and arthritis were more common among the B blood type and Rh-positive group, respectively. Furthermore, there was no relation between ABO and Rh blood group and rheumatoid factor (RF) and anti-Cyclic Citrullinated Peptide (anti-CCP) seropositivity. Moreover, there was no difference in distribution of blood groups in RA and SLE patients. Conclusion: The higher frequency of blood group B in hemolytic anemia, and positive Rh in arthritis in lupus patients, develop the hypothesis of probable role of ABO blood group antigen in some manifestations of lupus. |
| نویسندگان مقاله |
| Amir Nik
Rheumatic Diseases Research Center, Quaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
| Zahra Mirfeizi
Rheumatic Diseases Research Center, Quaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
| Zahra Rezaieyazdi
Rheumatic Diseases Research Center, Quaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
| Mandana Khodashahi
Rheumatic Diseases Research Center, Quaem Hospital, Mashhad University of Medical Sciences, Mashhad, Iran
| Shahin Danevash
Qazvin Metabolic Disease Research Center, Qazvin University of Medical Sciences, Qazvin, Iran
| Mohammad Sobhan Sheikh Andalibi
ُSudent of medicine, Rheumatic Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
| Mahnaz Abbasi
Qazvin Metabolic Disease Research Center, Qazvin University of Medical Sciences, Qazvin, Iran.
| Maryam Sahebari
Rheumatic Diseases Research Center, Mashhad University of Medical Sciences, Mashhad, Iran
|