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Caspian Journal of Internal Medicine، جلد ۱۲، شماره ۴، صفحات ۶۱۳-۶۱۷
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Adrenocortical carcinoma in a patient with Neurofibromatosis type 1: a case report |
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| چکیده انگلیسی مقاله |
Background: Neurofibromatosis type 1 (NF-1) is a genetic disorder. A heterogeneous group of benign and malignant neoplasms are associated with NF-1. Adrenocortical carcinoma (ACC) is an extremely rare invasive malignancy. The association of ACC with NF1 is not well understood. Case Presentation: We report a case of ACC in the context of NF1 in a 39- year-old woman who referred with the chief complaint of a mass in left abdomen. A left adrenal lesion was diagnosed by CT scan. Biochemical tests showed no abnormality. Adrenalectomy was done and histological and immunohistochemical findings confirmed ACC. Due to the absence of metastasis, clinical stage II was considered for the tumor. On follow-up after six months, she was still alive and well and with no evidence of metastasis. The age of patient and lack of secretion of adrenal cortical hormones in this case were unlike most ACCs. Conclusion: Also, modified Weiss score for malignancy of adrenocortical neoplasms, clinical staging system and different modality of treatment is discussed. |
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| کلیدواژه‌های انگلیسی مقاله |
Adrenocortical Carcinoma, Neurofibromatosis 1, Adrenal Glands, Adrenal Cortex Neoplasms |
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| نویسندگان مقاله |
| Mohammad Najafi-Semnani
Department of Urology, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran
| Mahdieh Rajabi-Moghaddam
Department of Pathology, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran
| Hamid Abbaszadeh
Department of Oral and Maxillofacial Pathology, School of Dentistry, Birjand University of Medical Sciences, Birjand, Iran
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| نشانی اینترنتی |
http://caspjim.com/browse.php?a_code=A-10-2010-2&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Oncology |
| نوع مقاله منتشر شده |
case report |
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