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Caspian Journal of Internal Medicine، جلد ۱۲، شماره ۳، صفحات ۲۸۳-۲۸۹
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Cutaneous pseudolymphoma: A clinicopathological study and immunohistochemical patterns |
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| چکیده انگلیسی مقاله |
Background: Cutaneous pseudolymphoma can histologically and clinically simulate various types of cutaneous lymphoma. We conducted the current study to evaluate the clinicopathological and immunohistochemical (IHC) aspects of cutaneous pseudolymphoma (PSL). Methods: 30 cases of cutaneous PSL were selected from the archives of 2013-2017 in Shahid Faghihi Hospital pathology lab, Shiraz University of Medical Sciences. Available clinical data, histopathological features and IHC findings were statistically analyzed. Results: The female: male ratio was 2:1 and the median age was 47±14.9 years. The lesions were located on the head and neck 26 (86.7%), trunk 2 (6.7%) and extremities 2 (6.7%). 23 (76.7%) cases had nodular pattern, while 7 (23.3%) showed diffuse pattern. The grenz zone was seen in 24 (80%) cases. Sixteen (53.3%) cases showed top heavy infiltration, 11 (36.7%) showed the same distribution of infiltration at the superficial and deep dermis, often involving the subcutaneous fat and 3(10%) showed bottom heavy infiltration. In IHC, 11(36.6%) cases showed the B cell type, 10 (33.3%) T cell type and 9 (30%) mixed type (B and T cells). Conclusion: None of the cases was suspicious for cutaneous lymphoma, applying IHC staining. Gender distribution, and the site of cutaneous lesions were similar to previous studies. The most common histological subtype was nodular, while the B-cell cutaneous pseudolymphoma was slightly more common compared to the T-cell type. |
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| کلیدواژه‌های انگلیسی مقاله |
Cutaneous, Pseudolymphoma, Immunohistochemistry. |
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| نویسندگان مقاله |
| Fatemeh Sari Aslani
Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
| Mozhdeh Sepaskhah
Molecular Dermatology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
| Akbar Safaei
Department of pathology, Shiraz University of Medical Sciences, Shiraz, Iran
| Seddigheh Jashounia Hormozi
Department of pathology, Shiraz University of Medical Sciences, Shiraz, Iran
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| نشانی اینترنتی |
http://caspjim.com/browse.php?a_code=A-10-1602-1&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Pathology |
| نوع مقاله منتشر شده |
Original Article |
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