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Caspian Journal of Internal Medicine، جلد ۱۲، شماره ۲، صفحات ۱۵۵-۱۶۱
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
The serum lipid profile of Parkinson's disease patients: A study from the Northwest of Iran |
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| چکیده انگلیسی مقاله |
Background: Parkinson's disease (PD) is defined as a long-lasting, neurological illness. Low levels of serum lipid fractions are related with a high risk of PD. Current investigation was designed to evaluate the concentration blood lipid fractions in patients suffering from PD and compared with healthy subjects. Methods: This case-control study was conducted from February 2016 to September 2018 in Tabriz University of Medical Sciences, Tabriz, Iran. The present investigation consisted of 75 persons who had PD and 75 normal people. The blood levels of lipid fractions were measured by concentrations of total cholesterol (TC), serum triglycerides (TG), low-density lipoprotein (LDL-C), high-density lipoprotein (HDL-C), and total cholesterol. The results were analyzed with SPSS software using Kolmogorov-Smirnov, chi-square, and student's t-test. Results: Serum level of TG was remarkably lower in patients with PD (111.92±8.75 mg/dL) compared with healthy subjects (123.64±9.97 mg/dL, P=0.008). Furthermore, we saw an important difference in the level of LDL-C (P=0.001) and TC (P=0.004) between the two groups. However, there was not any observed meaningful difference in the serum concentrations of HDL-C between the studied groups (P=0.135). Conclusion: Our results showed that the serum concentration of TG, LDL-C, and TC are noticeably lower in the PD suffering patients. Further investigations are needed to provide comprehensive information on the participants' cognitive layout and subsequent actions. |
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| کلیدواژه‌های انگلیسی مقاله |
Triglycerides, LDL, HDL, Cholesterol, Parkinson Diseases |
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| نویسندگان مقاله |
| Samira Saedi
Department of Medicine Microbiology, Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran
| Mohsen Hemmati-Dinarvand
Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
| Haleh Barmaki
Shahid Beheshti University of Medical Sciences, Tehran, Iran.
| Zohreh Mokhtari
Department of Laboratory Medicine, Faculty of Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
| Hadis Musavi
Student Research Committee, Babol University of Medical Sciences, Babol Iran
| Mohamad Valilo
Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
| Ali Mota
Department of Clinical Biochemistry and Laboratory Medicine, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
| Soleiman Mahjoub
Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran
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| نشانی اینترنتی |
http://caspjim.com/browse.php?a_code=A-10-71-7&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Biochimestry |
| نوع مقاله منتشر شده |
Original Article |
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