|
|
Caspian Journal of Internal Medicine، جلد ۱۲، شماره ۲، صفحات ۲۰۷-۲۱۵
|
|
|
| عنوان فارسی |
|
|
| چکیده فارسی مقاله |
|
|
| کلیدواژه‌های فارسی مقاله |
|
|
| عنوان انگلیسی |
Rectal Diclofenac versus High-Dose Rectal Acetaminophen in Children: a randomized clinical trial |
|
| چکیده انگلیسی مقاله |
Background: Fever is the most common complaint among the children admitted to health care centers. The aim of this study was to compare the anti-pyretic effect of diclofenac and high dose acetaminophen suppository in 1 to 6 years old children. Methods: This double-blind clinical trial study was performed on 1-6-year-old children hospitalized in 17th Shahrivar Teaching Hospital, Rasht, Iran. Children were divided into two groups of 45 using a block randomization design. The first group received a high dose of acetaminophen suppository at a dose of 30 mg/kg and the second group received a diclofenac suppository at a dose of 1 mg/kg. The rectal temperature of the patients was measured using a digital thermometer at the time of drug administration, and one and three hours after that. Results: 90 children were studied in two groups of 45 each. Temperature changes in the diclofenac group were significantly greater than the acetaminophen group, so from zero to 3 hours after administering diclofenac, the temperature decreased to 1.76±0.95°C. This reduction was lower in acetaminophen group (1.26±0.49°C, P=0.019). Conclusion: Both acetaminophen and diclofenac suppositories significantly reduced the rectal temperature. However, the effect of rectal diclofenac on reducing temperature is more than rectal acetaminophen. |
|
| کلیدواژه‌های انگلیسی مقاله |
acetaminophen, diclofenac, fever, rectal, suppository |
|
| نویسندگان مقاله |
| Houman Hashemian
Pediatric Diseases Research Center (PDRC), Guilan University of Medical Sciences, Rasht, Iran
| Marzie Fallah Khodadoost
Pediatric Diseases Research Center (PDRC), Guilan University of Medical Sciences, Rasht, Iran.
|
|
| نشانی اینترنتی |
http://caspjim.com/browse.php?a_code=A-10-1805-1&slc_lang=en&sid=1 |
| فایل مقاله |
فایلی برای مقاله ذخیره نشده است |
| کد مقاله (doi) |
|
| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Pediatrics |
| نوع مقاله منتشر شده |
Original Article |
|
|
|
برگشت به:
صفحه اول پایگاه |
نسخه مرتبط |
نشریه مرتبط |
فهرست نشریات
|