Caspian Journal of Internal Medicine، جلد ۱۲، شماره ۱، صفحات ۷۰-۷۶

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عنوان انگلیسی Relationship between sperm parameters and clinical outcomes of Intra Uterine Insemination (IUI)
چکیده انگلیسی مقاله Background: Intrauterine insemination (IUI) is a widely utilized method for treating the infertile couples. The aim of the present study was to determine the pregnancy and abortion rates after IUI and to examine the relationship of sperm parameters with these rates. Methods: This retrospective study was performed on 911 infertile couples undergoing IUI treatment in Shahid Akbarabadi IVF Centre from May 2017 to May 2019. To evaluate the correlation of sperm parameters with the clinical pregnancy and abortion rates, odds ratio (OR) with 95% confidence intervals (CI) was calculated. Results: In this study, the pregnancy rate following IUI was 15.7% (143/911), and among women who achieved pregnancy, the abortion rate was 42.0% (60/143). According to the multiple logistic regression analysis, none of the sperm parameters was associated with the pregnancy rate. Couples with either male or female factor infertility etiologies were more likely to get pregnant than those with unexplained infertility. Regarding the abortion rate, multiple logistic regression analysis revealed that normal sperm count was related to a lower abortion rate (adjusted OR=0.25, 95% CI=0.07–0.91). Conclusion: The present study did not reveal a significant relationship between none of the sperm parameters and pregnancy rate after IUI treatment. However, among women who got pregnant, continuation of the pregnancy was associated with the normal sperm count. Furthermore, analysis of all semen parameters together in comparison to one parameter alone might be more accurate to predict pregnancy or abortion. Further prospective cohort studies with a large number of couples are required.
کلیدواژه‌های انگلیسی مقاله Intrauterine Insemination, Pregnancy, Abortion, Sperm Parameters, Infertility

نویسندگان مقاله | Fatemeh Mohammadi
Department of Anatomy, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran


| Zohreh Mehdinia
Department of Anatomy, Faculty of Medicine, International campus, Iran University of Medical Sciences, Tehran, Iran


| Samaneh Ghasemi
Shahid Akbarabadi Clinical Research Development Unit (ShACRDU), Iran University of Medical Science, Tehran, Iran


| Zahra Zolfaghari
Reproductive Epidemiology Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, Iran


| Fatemeh Sadat Amjadi
Shahid Akbarabadi Clinical Research Development Unit (ShACRDU), Iran University of Medical Science, Tehran, Iran


| Mahnaz Ashrafi
Shahid Akbarabadi Clinical Research Development Unit (ShACRDU), Iran University of Medical Science, Tehran, Iran


| Zahra Zandieh
Shahid Akbarabadi Clinical Research Development Unit (ShACRDU), Iran University of Medical Science, Tehran, Iran



نشانی اینترنتی http://caspjim.com/browse.php?a_code=A-10-1664-1&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Obstetrics & Gynicology
نوع مقاله منتشر شده Original Article
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