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Caspian Journal of Internal Medicine، جلد ۱۲، شماره Case Supplement، صفحات ۳۶۳-۳۶۷
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Therapeutic challenge: Unusual coexistence of idiopathic central diabetes insipidus and diabetes mellitus in a male with vitiligo |
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| چکیده انگلیسی مقاله |
Background: Idiopathic central diabetes insipidus (DI) is a rare endocrine disorder that results from total or partial deficiency of vasopressin secretion. It is idiopathic when the cause is unknown, but in many cases, is associated with autoimmune disorders. Case presentation: We present the case of a 44-year-old male with vitiligo and a family history of diabetes mellitus and thyroid disease. The patient presented with polydipsia and polyuria greater than 8 L/day. After water deprivation test, the patient was diagnosed with partial central diabetes insipidus. Contrast-enhanced pituitary magnetic resonance imaging showed decreased brightness of the neurohypophysis and normal thickness of the pituitary stalk. Because desmopressin was not initially available, the patient was managed with chlorpropamide, carbamazepine, and hydrochlorothiazide, and afterwards substituted. During his outpatient checkups, he presented many episodes of polyuria, the last after 13 years, with polyuria of up to 15 L associated with weight loss, and abnormal blood glucose levels; anti-GAD 65 and IA-2 antibodies were negative. He was subsequently diagnosed with diabetes mellitus and received metformin and insulin; this latter was suspended in subsequent check-ups due to hypoglycemic episodes. Conclusion: We highlight the importance of treatment and adequate control of these pathologies, since they share similar clinical manifestations, can easily have electrolyte imbalance and represent a challenge for endocrinologists and internists. |
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| کلیدواژه‌های انگلیسی مقاله |
Central diabetes insipidus, diabetes mellitus, water deprivation test, vitiligo |
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| نویسندگان مقاله |
| Diego Moreno Marreros
Division of Endocrinology, Clínica Stella Maris, Lima, Perú
| Marcio José Concepción Zavaleta
National University of Trujillo, Faculty of Medicine, Trujillo, Perú
| Eilhart Jorge Garxia Villasante
Division of Endocrinology, Hospital Nacional Daniel Alcides Carrión, Lima, Perú
| Esteban Alberto Plasencia Dueñas
Division of Endocrinology, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Perú
| Sofia Ildefonso Najarro
Division of Endocrinology, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Perú
| José Carrion Rojas
Division of Endocrinology, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Perú
| Carmen Luisa Achahui Acurio
Division of Endocrinology, Hospital Nacional Guillermo Almenara Irigoyen, Lima, Perú
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| نشانی اینترنتی |
http://caspjim.com/browse.php?a_code=A-10-1980-1&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Endocrinology |
| نوع مقاله منتشر شده |
case report |
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