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Caspian Journal of Pediatrics، جلد ۷، شماره ۱، صفحات ۴۷۹-۴۸۷
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Short-term complications associated with exchange transfusion in neonates with severe hyperbilirubinemia |
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| چکیده انگلیسی مقاله |
Background and Objective: Neonatal jaundice is a common condition among neonates in the first few days of life and is a leading cause of admission among neonates. The aim of this study was to investigate the most common risk factors associated with severe neonatal hyperbilirubinemia (NNH) and short-term complications of the exchange transfusion (ET). Methods: In this retrospective study, the medical records of newborns < 28 days with severe hyperbilirubinemia who underwent ET during 2015-2018 were analyzed. Medical records and files were searched using the keyword "exchange transfusion". The clinical and demographic characteristics of the study population as well as the short-term complications of ET were descriptively analyzed. Findings: Totally, 74 newborns with the mean age of 5.6 ± 3.4 days were included in the current study. The baseline mean peak total serum bilirubin (TSB) was 25.8 ± 5.7 mg/dl. In neonates, the ABO incompatibility was the most frequent cause of severe hyperbilirubinemia requiring ET (54.1%), followed by sepsis (39.2%). Moreover, 57.7% of neonates developed complications secondary to ET. The most common complication was hyperglycemia (71.6%), followed by thrombocytopenia (48.6%). Conclusion: Hemolysis and sepsis are common causes of NNH; therefore, the extensive screening and identification of the at-risk population can help decrease the incidence of severe NNH. Frequent monitoring of blood sugar and screening of thrombocytopenia before and after ET procedures are necessary to reduce adverse events. |
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| کلیدواژه‌های انگلیسی مقاله |
Exchange, Indirect Hyperbilirubinemia, Neonatal Jaundice, Newborn |
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| نویسندگان مقاله |
| Mahbod Kaveh
neonatal-perinatal medicine
| Emmanuel Adutwum
School of Medicine
| Mohammad Kaji Yazdi
Assistant Professor of Pediatric Hematology and Oncology, Tehran University of Medical Sciences, Tehran, Iran
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| نشانی اینترنتی |
http://caspianjp.ir/browse.php?a_code=A-10-178-1&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
عمومی |
| نوع مقاله منتشر شده |
پژوهشی |
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