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Caspian Journal of Pediatrics، جلد ۶، شماره ۲، صفحات ۴۳۰-۴۳۳
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Death of a steroid-dependent nephrotic syndrome patient taking levamisole: A case report |
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| چکیده انگلیسی مقاله |
Background: Levamisole is an anthelmintic drug used in the treatment of patients with a diagnosis of steroid-dependent nephrotic syndrome. Skin rash has been reported as a drug side effect, but adverse events are really rare. Case report: The case presented in this article was a 14-year-old boy with steroid-dependent nephrotic syndrome, treated with levamisole due to frequent relapse. He was admitted with rash, weakness, fatigue, fever, and weight loss. Levamisole was discontinued, and the patient's condition improved in the following two weeks. One year later, the nephrotic syndrome relapsed, and he received prednisolone and levamisole. He was admitted to the hospital six months after re-administration of these drugs because of vasculopathy, and unfortunately, he died due to disseminated intravascular coagulation (DIC). Conclusions: Although levamisole is a suitable and cost-effective therapy for remission maintenance in steroid-dependent nephrotic syndrome, it is highly recommended to discontinue the drug without re-administration in case of reoccurring adverse effects, especially skin rash and systemic reaction, in addition to close monitoring of the patients under treatment. |
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| کلیدواژه‌های انگلیسی مقاله |
Child, Levamisole, Nephrotic Syndrome, Rash, Vasculopathy |
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| نویسندگان مقاله |
| mahbobeh neamatshahi
Department of community Medicine, Faculty of Medicine, Research Center Social Determinants health, Sabzevar University of Medical Sciences, Iran
| Elham Navipour
Department of Anesthesiology, Faculty of Paramedicine, Sabzevar University of Medical Sciences, Sabzevar, Iran
| Zahra Barabadi
Department of Tissue Engineering, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.
| Aghil Keykhosravi
Department of pediatrics, Faculty of Medicine, Sabzevar University of Medical Sciences, Sabzevar, Iran
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| نشانی اینترنتی |
http://caspianjp.ir/browse.php?a_code=A-10-153-1&slc_lang=en&sid=1 |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
عمومی |
| نوع مقاله منتشر شده |
گزارش مورد |
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