Caspian Journal of Internal Medicine، جلد ۱۶، شماره ۴، صفحات ۳-۰

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عنوان انگلیسی A systematic review and meta-analysis of the prevalence of celiac disease in migraine patients
چکیده انگلیسی مقاله Background: Celiac disease (CD) is an autoimmune disease with gluten intolerance, which is associated with various neurological disorders. Patients may present with signs of malabsorption or extraintestinal involvement or be completely asymptomatic. It is usually unknown how common celiac disease is in migraine patients. Therefore, the purpose of this study was to investigate the prevalence of CD in migraine patients using a systematic review and meta-analysis.
Methods: PRISMA guidelines created a framework for the construction of this review article. Two researchers examined databases such as Scopus, PubMed, Web of Science, and Google Scholar to review the literature, with no limitations on time until May 2024. The Cochran's test and the I2 index were used for evaluation. The heterogeneity of data studies was analyzed using Stata14.2 software, and p<0.05 was considered significant.
Results: A total of 6 articles including 14526 migraine patients were comprised in the meta-analysis. The overall prevalence of CD in migraine patients was estimated to be (2% (95% CI: 0%-5%, I2=75.37, P=0.001)). Also, the Odds of CD disease in migraine patients compared to non-migraine patients was estimated to be equal (2.20 (95% CI: 0.87-5.54, I2=48.4, P=0.121)). Additionally, the majority of the research was conducted in Europe.
Conclusions: Although the small amount of research accomplished in this particular situation, our data indicate a relatively low prevalence of CD in migraine patients. Therefore, more frequent and thorough research in this field is advised. Patients with migraines experienced fewer attacks when they received gluten-free diets and were screened for celiac disease.

 
کلیدواژه‌های انگلیسی مقاله Coeliac disease, Gluten Sensitive Enteropathy, Migraine, Systematic review , Meta-analysis

نویسندگان مقاله | Gholamreza Kalvandi
Associate Professor of Pediatrics Gastroenterology, Department of Pediatrics, Hamadan University of Medical Sciences, Hamadan, Iran


| Naser Naser Nasiri
School of Health, Jiroft University of Medical Sciences, Jiroft, Iran


| Parya Jangipour Afshar
PhD Candidate in Epidemiology, Department of Biostatistics and Epidemiology, Faculty of Public Health, Kerman University of Medical Sciences, Kerman, Iran


| Hosna Ghaderi
Department of Laboratory Sciences, Faculty of Paramedical, Kurdistan University of Medical Sciences, Kurdistan, Iran


| Farzad Faizi
Department of Epidemiology and Biostatistics, Faculty of Medicine, Kurdistan University of Medical Sciences, Kurdistan, Iran


| Shoboo Rahmati
Department of Epidemiology and Biostatistics, Faculty of Medicine, Kurdistan University of Medical Sciences, Kurdistan, Iran



نشانی اینترنتی http://caspjim.com/browse.php?a_code=A-10-609-4&slc_lang=en&sid=1
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Neurology
نوع مقاله منتشر شده Review Article
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