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Caspian Journal of Internal Medicine، جلد ۸، شماره ۴، صفحات ۲۸۹-۲۹۵
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژههای فارسی مقاله |
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| عنوان انگلیسی |
Does the low-density lipoprotein cholesterol play a key role in predicting metabolic syndrome in the Iranian adult population? |
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| چکیده انگلیسی مقاله |
Background: The low density lipoprotein cholestrol (LDL-C) has an important role in the pathogenesis of cardiovascular disease but its association and predictive accuracy with metabolic syndrome (MetS) remains controversial. The objective of this study was to investigate the association and predictive ability of LDL-C with MetS. Methods: We analyzed the data from a population-based cross-sectional study conducted on representative samples of an Iranian adult population. The demographic data, anthropometric measures and the lipid profiles were measured with standard methods, and MetS was diagnosed by ATP III criteria. Logistic regression model and ROC analysis were used to estimate the predictive accuracy of LDL-C and its association with MetS. Results: The mean age (±SD) of participants with and without MetS was 47.6±12.5 years and 39.1±12.9 years, respectively (p=0.001). All anthropometric measures (body mass index, waist circumference, waist to hip ratio, waist to height ratio), systolic blood pressure, total cholesterol, triglycerides and fasting blood glucose were significantly higher in MetS, but a significantly higher difference in LDL-C was observed only in women. Accuracy of LDL-C in predicting MetS for men and women was 0.48 (95% CI: 0.43-0.54) and 0.55 (95% CI: 0.51-0.60), respectively. The unadjusted and adjusted odds ratios of different quartiles of LDL-C compared with 1st quartile did not reach to a significant level. Conclusion: Serum LDL-C level is not significantly associated with MetS but exhibits a weak ability in predicting MetS in women. |
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| کلیدواژههای انگلیسی مقاله |
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| نویسندگان مقاله |
کریم الله حاجیان تیلکی | karimollah hajian tilaki
social determinant health research center, health research institute, babol university of medical sciences, babol, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)
بهزاد حیدری | behzad heidari
mobility impairment research center, health research institute, babol university of medical sciences, babol, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)
عارفه حاجیان تیلکی | arefeh hajian tilaki
guilan university of medical sciences
سازمان اصلی تایید شده: دانشگاه علوم پزشکی گیلان (Guilan university of medical sciences)
علیرضا فیروزجاهی | alireza firouzjahi
department of orthodontics, guilan university of medical sciences, rasht, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی گیلان (Guilan university of medical sciences)
افسانه بختیاری | afsaneh bakhtiari
fatemeh zahra infertility and reproductive health research center, health research institute, babol university of medical sciences, babol, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)
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| نشانی اینترنتی |
http://caspjim.com/browse.php?a_code=A-10-133-3&slc_lang=en&sid=en |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/176/article-176-449001.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Health |
| نوع مقاله منتشر شده |
Original Article |
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