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International Journal of Molecular and Cellular Medicine، جلد ۶، شماره ۲، صفحات ۱۰۹-۱۲۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Isolation and Characterisation of Actinobacteria from Algerian Sahara Soils with Antimicrobial Activities |
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| چکیده انگلیسی مقاله |
Extreme ecosystems can be a source of untapped micro-organisms able to produce novel bioactive compounds of industrial interest. Consequently, in this work, 32 Actinomycetes were isolated from 6 soil samples collected from Algerian Sahara in searching for untapped producers of novel antimicrobial compounds. All the isolates were further subjected to antimicrobial screening against pathogenic bacteria, yeast and fungi. The obtained results indicated that three of the isolates (named C, MS1 and 10) showed antimicrobial activities against most of the tested pathogenic micro-organisms. Therefore, these three promising isolates, previously identified as Streptomyces by morphological, biochemical and physiological methods, were selected for their subsequent identification by the whole cell matrix assisted laser desorption ionization time of flight mass spectrometry (MALDI-TOF MS) analysis. Thus, the isolates C, MS1 and 10 were identified as Streptomyces violaceoruber B263 UFL, Streptomyces albus B262 UFL, and Streptomyces badius B192 UFL, respectively. These results pointed out Actinomycetes from Sahara soils as potential sources of novel antimicrobial compounds. Also, MALDI-TOF MS showed to be a robust technique for bacteria identification. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
حریر محمد | harir mohamed
biology of microorganisms and biotechnology laboratory, university of oran 1 ahmed ben bella, oran, algeria.
bellahcene miloud | bellahcene miloud
faculty of sciences, natural and life sciences department, mohamed boudiaf university, m’sila, algeria.
fortas زهره | fortas zohra
biology of microorganisms and biotechnology laboratory, university of oran 1 ahmed ben bella, oran, algeria.
جوز maría جوز maría گارسیا arenzana | josé maría josé maría garcía arenzana
microbiología, hospital universitario donostia, donostia-san sebastián, spain.
آنتونیو veloso | antonio veloso
polymat, university of the basque country upv ehu, donostia-san sebastian, spain.
سوسانا رودریگز کوتو | susana rodriguez couto
ceit-ik4, water amp; health division, donostia-san sebastian, spain.
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| نشانی اینترنتی |
http://ijmcmed.org/browse.php?a_code=A-10-1135-1&slc_lang=en&sid=en |
| فایل مقاله |
اشکال در دسترسی به فایل - ./files/site1/rds_journals/245/article-245-449384.pdf |
| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Other |
| نوع مقاله منتشر شده |
Original Article |
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