| چکیده انگلیسی مقاله |
Background: Recurrent aphthous stomatitis (RAS) is the most common inflammatory ulcerative condition of oral cavity. The aim of this study was to compare the levels of the salivary Malondialdehyde (MDA) and total antioxidant capacity (TAC) and blood parameter in RAS versus healthy controls. Methods: This case-control study consisted of 28 patients with RAS and 28 age and sex -matched control without RAS. Cell blood count was assessed by sysmex system, serum iron and total iron binding capacity was measured by standard laboratory kit and for ferritin ELISA kit was utilized. Salivary TAC and MDA level determined using FRAP and TBARS method respectively. Statistical analysis was performed using SPSS Version 21, chi-square test was used to compare proportions, and student’s t-test and Mann Whitney U-test were used for the comparison of quantitative variables Results: Salivary MDA level was significantly higher (p< 0.001) and TAC level was significantly lower (p< 0.042) in RAS as compared with the control group. Also, serum ferritin level was significantly higher in RAS patients (p< 0.008). Conclusion: These findings indicate the alteration of oxidant/antioxidant status was observed in recurrent aphthous stomatitis, may be also associated with changing several hematinic parameters in this study. The finding maybe helpful to clarify the etiologies of RAS and possibely to improve the management or preventive options. |
| نویسندگان مقاله |
ندا بابایی | neda babaee
department of oral medicine, faculty of dentistry, babol university of medical sciences, babol iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)
حامد حسین کاظمی | hamed hosseinkazemi
department of oral medicine, faculty of dentistry, babol university of medical sciences, babol iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)
مهدی پورامیر | mahdi pouramir
cellular and molecular biology research center, babol university of medical sciences, babol, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)
اویس خاکباز بابلی | oveis khakbaz baboli
department of oral medicine, faculty of dentistry, babol university of medical sciences, babol iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)
مایده صالحی | maede salehi
department of oral medicine, faculty of dentistry, mazandaran university of medical sciences, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی مازندران (Mazandaran university of medical sciences)
فاطمه خدیر | fatemeh khadir
department of biochemistry, babol university of medical sciences, babol, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)
علی بیژنی | ali bijani
social determinant of health research center, babol university of medical sciences, babol, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)
مهسا مهریاری | mahsa mehryari
department of oral medicine, faculty of dentistry, ardebil university of medical sciences, ardebil, iran.
|