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Caspian Journal of Internal Medicine، جلد ۶، شماره ۴، صفحات ۱۸۷-۱۹۵
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Efficacy of probiotic use in acute rotavirus diarrhea in children: A systematic review and meta-analysis |
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| چکیده انگلیسی مقاله |
Background: Probiotic therapies with different strains demonstrated some beneficial effects, although some studies did not show any significant effects. This study assessed systematically the current knowledge on the effect of probiotic bacteria on duration of in acute rotavirus diarrhea in children compared with control. Methods: The PubMed, Cochrane Controlled Trial Register (CCTR) and Ovid (Wolters Kluwer Health) were searched between 1980 to June 15, 2013. Randomized controlled trials including the administration of probiotics for treatment of rotavirus diarrhea in infants and children were reviewed. Results: A total number of 1244 articles were found through the aforementioned search. 203 articles were selected after the first screening of title and abstract. The intervention group included subjects who received probiotic strains and dosage in any conditions. Placebo or any similar vehicle without probiotic was used in the controlled trials. Finally, 14 articles were selected. The outcomes from each study were considered in the duration of diarrhea. Statistical analyses were performed with Stata software. The pooled estimate of efficacy of probiotics in prevention or treatment of disease yielded in all studies a mean difference of 0.41 (CI 95%: -0.56 to –0.25 p< 0.001). The pooled estimate of efficacy of lactobacillus rhamnosus GG and other probiotics significantly reduced the duration of diarrhea. Among trials, the overall reduction of LGG was 0.47 (CI 95%: -0.80 to -0.14 P= 0.020). Conclusion: In conclusion, probiotics exert positive effect in reducing the duration of acute rotavirus diarrhea compared with control. |
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| کلیدواژه‌های انگلیسی مقاله |
Probiotics, Rotavirus, Acute Diarrhea, Children |
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| نویسندگان مقاله |
الهه احمدی | elaheh ahmadi
young researchers and elites club, science and research branch, islamic azad university, tehran, iran
سازمان اصلی تایید شده: دانشگاه آزاد اسلامی علوم و تحقیقات (Islamic azad university science and research branch)
رضا علیزاده نوایی | reza alizadeh navaei
molecular and cell biology research center, mazandaran university of medical science, sari, iran
سازمان اصلی تایید شده: دانشگاه مازندران (Mazandaran university)
محمد صادق رضایی | mohammad sadegh rezai
department of pediatric infectious disease, antimicrobial resistant nosocomial infection research center, bou ali sina hospital, pasdaran boulevard, sari, iran
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| نشانی اینترنتی |
http://www.caspjim.com/browse.php?a_code=A-10-200-1&slc_lang=en&sid=en |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Pediatrics |
| نوع مقاله منتشر شده |
Review Article |
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