Caspian Journal of Internal Medicine، جلد ۶، شماره ۲، صفحات ۶۲-۶۶
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عنوان انگلیسی Relationship between Helicobacter pylori infection (HP) and bone mineral density (BMD) in elderly people
چکیده انگلیسی مقاله Background: Low bone mass is a frequent complication of chronic inflammatory disease. The pathogenesis of osteoporosis in chronic inflammatory disease may be secondary to releases of cytokines such as TNF-a and IL6. Chronic gastritis due to helicobacter pylori (HP) infection may lead to decreased bone mineral density (BMD) and predispose patients to osteoporosis. The objective of this study was to determine the BMD status in HP positive patients with gastritis versus HP negative cases. Methods: In this cross-sectional study, we enrolled 967 participants aged 60 years old and more from Amirkola Health Study Ageing Project. Seven-hundred and fifty eight HP positive and 209 HP negative patients were analyzed. BMD was measured by dual-energy x-ray absorptiometry (DXA) method in the spine and femoral neck in all participants. Results: The mean age in HP+ and HP- negative patients was 68.3±6.8 and 69.3±7.4 years, respectively. BMD g/cm2 in the spine and femoral neck did not differ between the two groups (P=0.19 and 0.22 respectively). The prevalence of osteoporosis did not also differ across the two groups as well. There was no relationship between the level of antibodies against HP and BMD.Conclusion: According to the findings of this study, H. pylori infection is not associated with BMD changes in the elderly population.
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نویسندگان مقاله مهدیه fotouk کیایی | mahdiye fotouk kiai
department of internal medicine, babol university of medical sciences, babol, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

سید رضا حسینی | seyed reza hoseini
social determinates of health research center, health research institute, babol university of medical sciences babol, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

ندا مفتاح | neda meftah
. department of internal medicine, babol university of medical sciences, babol, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

رضا قدیمی | reza ghadimi
social determinates of health research center, health research institute, babol university of medical sciences babol, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

علی بیژنی | ali bijani
social determinates of health research center, health research institute, babol university of medical sciences babol, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

حاجی قربان نورالدینی | hajighorban noreddini
department of radiology, babol university of medical sciences, babol, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

حمیدرضا نعمت اللهی | hamidreza nematollahi
department of internal medicine, babol university of medical sciences, babol, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

جواد شکری شیروانی | javad shokri shirvani
department of internal medicine, babol university of medical sciences, babol, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

نشانی اینترنتی http://www.caspjim.com/browse.php?a_code=A-10-120-3&slc_lang=en&sid=en
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Gastroentrology
نوع مقاله منتشر شده Original Article
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