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Caspian Journal of Internal Medicine، جلد ۶، شماره ۲، صفحات ۸۷-۹۲
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چکیده فارسی مقاله |
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کلیدواژههای فارسی مقاله |
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عنوان انگلیسی |
Comparison of the analgesic effect of intravenous paracetamol/midazolam and fentanyl in preparation |
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چکیده انگلیسی مقاله |
Background: Although some patients can tolerate colonoscopy procedure using fentanyl/ midazolam without any sedation and analgesic requirements but some patients may require additional sedation with benzodiazepines. We performed the present study to compare the effect of paracetamol/midazolam with fentanyl/ midazolam. Methods: In a clinical trial, 96 patients aged 18 to 75 years old, who were candidate for elective colonoscopy assigned consecutively into two groups as paracetamol/midazolam and fentanyl/midazolam. The first group received 1 gr paracetamol 45 minutes before colonoscopy and 0.5 mg/kg midazolam 5 minutes before colonoscopy whereas the second group received 04- 0.5-1 mcg/kg fentanyl 3 minutes before colonoscopy and similar dose of midazolam. The two groups were compared in regard to patient intensity, discomfort, a colonoscopist and, patient satisfaction and rescue dose of propofol during colonoscopy and vital signs. Results: There was no significant difference between the two groups for patient pain score, colonoscopist satisfaction, patient satisfaction and rescue dose of propofol (P=0.817, 0.978, 0.460, and 0.104, respectively). The incidence of apnea was greater in fentanyl group (P=0.045). After adjusting for age and education, there was also no significant difference between the two groups. Conclusion: This study indicates that paracetamol can be considered as an alternative drug regimen in preparation of colonoscopy. |
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کلیدواژههای انگلیسی مقاله |
Paracetamol, Fentanyl, Colonoscopy, Analgesia |
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نویسندگان مقاله |
عباسعلی احمدی | abbasali ahmadi department of internal medicine, babol university of medical science, babol, iran
پرویز امری | parviz amri department of intensive care, babol university of medical sciences, babol, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)
جواد شکری شیروانی | javad shokri shirvani department of internal medicine, babol university of medical science, babol, iran
کریم الله حاجیان | karimollah hajian department of social medicine and health, babol university of medical sciences, babol, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)
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نشانی اینترنتی |
http://www.caspjim.com/browse.php?a_code=A-10-237-1&slc_lang=en&sid=en |
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کد مقاله (doi) |
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زبان مقاله منتشر شده |
en |
موضوعات مقاله منتشر شده |
Gastroentrology |
نوع مقاله منتشر شده |
Original Article |
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