Caspian Journal of Internal Medicine، جلد ۶، شماره ۲، صفحات ۸۷-۹۲

عنوان فارسی
چکیده فارسی مقاله
کلیدواژه‌های فارسی مقاله

عنوان انگلیسی Comparison of the analgesic effect of intravenous paracetamol/midazolam and fentanyl in preparation
چکیده انگلیسی مقاله  Background: Although some patients can tolerate colonoscopy procedure using fentanyl/ midazolam without any sedation and analgesic requirements but some patients may require additional sedation with benzodiazepines. We performed the present study to compare the effect of paracetamol/midazolam with fentanyl/ midazolam. Methods: In a clinical trial, 96 patients aged 18 to 75 years old, who were candidate for elective colonoscopy assigned consecutively into two groups as paracetamol/midazolam and fentanyl/midazolam. The first group received 1 gr paracetamol 45 minutes before colonoscopy and 0.5 mg/kg midazolam 5 minutes before colonoscopy whereas the second group received 04- 0.5-1 mcg/kg fentanyl 3 minutes before colonoscopy and similar dose of midazolam. The two groups were compared in regard to patient intensity, discomfort, a colonoscopist and, patient satisfaction and rescue dose of propofol during colonoscopy and vital signs. Results: There was no significant difference between the two groups for patient pain score, colonoscopist satisfaction, patient satisfaction and rescue dose of propofol (P=0.817, 0.978, 0.460, and 0.104, respectively). The incidence of apnea was greater in fentanyl group (P=0.045). After adjusting for age and education, there was also no significant difference between the two groups. Conclusion: This study indicates that paracetamol can be considered as an alternative drug regimen in preparation of colonoscopy. 
کلیدواژه‌های انگلیسی مقاله Paracetamol, Fentanyl, Colonoscopy, Analgesia

نویسندگان مقاله عباسعلی احمدی | abbasali ahmadi
department of internal medicine, babol university of medical science, babol, iran


پرویز امری | parviz amri
department of intensive care, babol university of medical sciences, babol, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

جواد شکری شیروانی | javad shokri shirvani
department of internal medicine, babol university of medical science, babol, iran


کریم الله حاجیان | karimollah hajian
department of social medicine and health, babol university of medical sciences, babol, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)


نشانی اینترنتی http://www.caspjim.com/browse.php?a_code=A-10-237-1&slc_lang=en&sid=en
فایل مقاله فایلی برای مقاله ذخیره نشده است
کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Gastroentrology
نوع مقاله منتشر شده Original Article
برگشت به: صفحه اول پایگاه   |   نسخه مرتبط   |   نشریه مرتبط   |   فهرست نشریات