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Caspian Journal of Internal Medicine، جلد ۶، شماره ۱، صفحات ۳-۸
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Muco-bioadhesive containing Ginger officinale extract in the management of recurrent aphthous stomatitis a double blind clinical study |
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| چکیده انگلیسی مقاله |
Background and objectives: Recurrent aphthous stomatitis (RAS) is the most common oral mucosal lesions in the general population. Various treatment modalities have been used but no specific therapy proved to be definitive. Ginger Officinale (ginger) indicated to have anti-inflammatory properties in herbal medicine. Thus, this study aimed to evaluate the efficacy of Gingerginger containing bioadhesive in treatment of aphthous ulcers. Material and Methods: This was a double-blinded placebo randomized controlled trial. Fifteen patients enrolled in this study. The clinical efficacy of the mucoadhessive on pain, inflammatory zone and ulcer's diameter in the test period was compared with that of the base treatment and no treatment periodss during 10 days of study. Results: Significant reduction in pain as observed on day 5 between placebo (using base bioadhesives) and no-treatment periods at the first phase of the study (4.53 vs. 3.27 p=0.038.( Reduction in inflamed halo diameters was significant on day 1 between no-treatment and ginger containing bioadhesives )46.73 vs 28.67 p=0.044). Other variables such as ulcer's diameter did not indicate any significant differences in both periods. Conclusion: This study indicated that ginger bioadhesive is capable to relieving pain of RAS. However, its efficacy on ulcer diameter, inflamed halo and healing time was not significantly different compared to the results of the placeb received period. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
پریا حق پناه | parya haghpanah
. department of periodontology, school of dentistry, babol university of medical sciences, babol, iran.
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)
علی اکبر مقدم نیا | aliakbar moghadamnia
. department of physiology amp;amp; pharmacology, babol university of medical sciences, babol, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)
امین ضرغامی | amin zarghami
student research committee, babol university of medical sciences, babol, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)
مینا مطلب نژاد | mina motallebnejad
dental materials research center, school of dentistry, babol university of medical sciences, babol, iran
سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)
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| نشانی اینترنتی |
http://www.caspjim.com/browse.php?a_code=A-10-101-1&slc_lang=en&sid=en |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Dentistry |
| نوع مقاله منتشر شده |
Original Article |
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