Caspian Journal of Internal Medicine، جلد ۵، شماره ۲، صفحات ۱۱۴-۱۱۷

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عنوان انگلیسی Glucose Tolerance and lipid profile changes after surgical menopause
چکیده انگلیسی مقاله Background: Bilateral salpingo-oophorectomy in women may lead to metabolic consequences in patients. This study was performed to determine the glucose tolerance and lipid profile after menopause resulting from bilateral salpingo-oophorectomy. Methods: From September 2011 to March 2013, 31 women participants aged 46-52 years who underwent hysterectomy and bilateral salpingo-oophorectomy for benign reasons were recruited. An oral glucose tolerance test (OGTT), triglyceride (TG), total cholesterol, low density lipoproteis (LDL), high density lipoprotein (HDL) was performed before and 6 months after surgery. Fasting insulin and 2-hour insulin levels, fasting insulin / glucose indexes and homeostasis model assessment HOMA indexes were also measured. Results: The mean age of the patients was 48.6±2.9 years.The mean 2-h glucose level in OGTT changed from 26.7 before surgery to 111.1 (P=0.030). The mean level of lipid profile before and after surgery for TG was 132.3 versus 181.2 (P=0.005), total cholesterol 177.4 versus 206.7 (P=0.0001) and LDL 98.4 versus 115.3 (P=0.003). The other variables showed no significant difference. Conclusion: The results indicate that lipid profile changes like increase of TG, total cholesterol and LDL should be considered before removing the ovary during hysterectomy in premenopausal women.
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نویسندگان مقاله شهلا یزدانی | shahla yazdani
fatemeh zahra infertility and reproductive health research center, babol university of medical sciences , babol, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

مجید شربتداران | majid sharbatdaran
department of pathology , babol university of medical sciences, babol , iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

محمد عابدی سماکوش | mohammad abedi samakoosh
department of internal medicine, mazandaran university of medical sciences, sari, iran.

سازمان اصلی تایید شده: دانشگاه علوم پزشکی مازندران (Mazandaran university of medical sciences)

زینت السادات بوذری | zinatossadat buzari
department of gynacology, babol university of medical sciences, babol, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)

زهرا مسعودی | zahra masoudi
. babol university of medical sciences, babol, iran

سازمان اصلی تایید شده: دانشگاه علوم پزشکی بابل (Babol university of medical sciences)


نشانی اینترنتی http://www.caspjim.com/browse.php?a_code=A-10-62-179&slc_lang=en&sid=en
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کد مقاله (doi)
زبان مقاله منتشر شده en
موضوعات مقاله منتشر شده Obstetrics & Gynicology
نوع مقاله منتشر شده Short Communication
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