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Caspian Journal of Internal Medicine، جلد ۴، شماره ۳، صفحات ۷۰۷-۷۱۱
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Urine methyl malonic acid levels in HIV-infected adults with peripheral neuropathy |
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| چکیده انگلیسی مقاله |
Background: Cobalamin deficiency and peripheral neuropathy (PN) are commonly seen in HIV-infected adults. The level of urine methylmalonic acid (UMMA), a reliable indicator of tissue cobalamin status, was determined in HIV infected subjects with and without PN to establish this association. Methods: One hundred and ninety-eight (198) consenting HIV infected subjects with and without PN were recruited for the study. UMMA level was determined by Cation Exchange High Performance Liquid Chromatography (HPLC) with Ultraviolet detector in 165 subjects. Simple proportions of patients with raised UMMA (defined as value> 3.4 mg in 24hr) were determined for each arm.Results: Among the 198 subjects studied, 146 had PN and 52 had no PN. From the 165 subjects whose UMMA was studied, raised UMMA was found in 76.6% (36 of 47) of subjects with no PN as compared with 53.4% (63 of 118) of those with PN (p=0.018).Conclusion: Cobalamin deficiency (measured by UMMA level) even though common in HIV infected subjects, may not be the cause of peripheral neuropathy in these subjects. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
adediran adewumi | adediran adewumi
akanmu علنی | akanmu alani
akinbami akinsegun | akinbami akinsegun
adeyemo titilope | adeyemo titilope
osunkalu وینسنت | osunkalu vincent
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| نشانی اینترنتی |
http://www.caspjim.com/browse.php?a_code=A-10-62-148&slc_lang=en&sid=en |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Infectious Diseases |
| نوع مقاله منتشر شده |
Original Article |
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