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Caspian Journal of Internal Medicine، جلد ۴، شماره ۳، صفحات ۷۲۷-۷۳۰
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژههای فارسی مقاله |
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| عنوان انگلیسی |
Evaluation of inhibitor antibodies in haemophilia A population |
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| چکیده انگلیسی مقاله |
Background: Inhibitory antibody to exogenous Factor VIII (FVIII) is a major complication of hemophilia treatment. This study was conducted to determine the prevalence of inhibitor antibody directed against FVIII.Methods: From May 2010 to May 2011, 52 patients with severe hemophilia A admitted in Amirkola Children’s Hospital were evaluated. Those who had abnormal mixing study, antibody against FVIII were measured. Data were collected and analyzed. Results: The age range of the patients was 4-60 years. The inhibitor antibody was seen in 9 (17.3%) patients. The mean age of patients with inhibitor at the time of diagnosis was 10.22 years (ranged 4-31 years). Old patients had more hemarthrosis than young patients. The mean level of inhibitor antibody was 8.47 Bethesda (ranged 2.3-29). Six patients had inhibitor antibody level ?5 Bethesda unit and three patients had inhibitor antibody level< 5 Bethesda unit.Conclusion: This study showed that the prevalence of inhibitor antibody in young patients is more than the old patients. |
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| کلیدواژههای انگلیسی مقاله |
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| نویسندگان مقاله |
حسن محمودی نشلی | hassan mahmoodi nesheli
آمره هادی زاده | amereh hadizadeh
علی بیژنی | ali bijani
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| نشانی اینترنتی |
http://www.caspjim.com/browse.php?a_code=A-10-62-151&slc_lang=en&sid=en |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Infectious Diseases |
| نوع مقاله منتشر شده |
Original Article |
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