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Caspian Journal of Internal Medicine، جلد ۳، شماره ۲، صفحات ۴۰۵-۴۰۹
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Steady state hemoglobin concentration and packed cell volume in homozygous sickle cell disease patients in Lagos, Nigeria |
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| چکیده انگلیسی مقاله |
Background: Sickle cell disease is a genetic disorder of hemoglobin causing myriad of pathology including anemia. The purpose of this study was to evaluate the baseline values of steady state hemoglobin and packed cell volume as a guide to managing the early recognition of hemolytic crises in sickle cell anemia. Methods: A cross-sectional study was conducted among the sickle cell patients attending the Sickle Cell clinic of Lagos State University Teaching Hospital, Ikeja. A blood sample of 4.5 ml blood was collected from each participant for hemoglobin concentration and packed cell volume. All blood samples were also screened for HIV and hemoglobin phenotypes were done using cellulose acetate hemoglobin electrophoresis at pH 8.6. Results: A total of 98 subjects in steady state were recruited, consisting of 53 (54.1%) females and 45 (45.9%) males. The overall means were 7.92±1.49 and 24.46±4.76 a female mean of 7.73±1.45 23.89±4.60, and a male mean of 8.14±1.54 and 25.14±4.91 were obtained for hemoglobin and packed cell volume, respectively. Sixty – nine of the 98 (70.40%) subjects have been previously transfused with blood. Conclusion: The mean hemoglobin concentration and packed cell volume in males was higher than females. The overall mean was lower than what was expected for age and sex. Over two-third of sickle cell anemia population had been transfused. |
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| کلیدواژه‌های انگلیسی مقاله |
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| نویسندگان مقاله |
akinsegun akinbami | akinsegun akinbami
dosunmu adedoyin | dosunmu adedoyin
adediran adewumi | adediran adewumi
oshinaike olajumoke | oshinaike olajumoke
phillip adebola | phillip adebola
وینسنت osunkalu | vincent osunkalu
olanrewaju arogundade | olanrewaju arogundade
oluwaseun adelekan | oluwaseun adelekan
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| نشانی اینترنتی |
http://www.caspjim.com/browse.php?a_code=A-10-62-84&slc_lang=en&sid=en |
| فایل مقاله |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
Infectious Diseases |
| نوع مقاله منتشر شده |
Original Article |
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