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Caspian Journal of Internal Medicine، جلد ۱، شماره ۱، صفحات ۹-۱۱
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| عنوان فارسی |
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| چکیده فارسی مقاله |
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| کلیدواژه‌های فارسی مقاله |
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| عنوان انگلیسی |
Efficacy of adding glutazone to the maximum dose of glibenclamide and metformin resistant on type 2 diabetic patients |
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| چکیده انگلیسی مقاله |
Background: To evaluate the efficacy of adding the glutazone to maximum dose of sulfonylurea and metformin in patients with poorly controlled type 2 diabetes. Methods: Ninety six patients with type 2 diabetes who had failed medical therapy with maximal-dosage of metformin and glibenclamide received glutazone. Fasting blood sugar (FBS), 2 hours postprandial (2hpp) glucose, hemoglobin A1C, cholesterol and HDL levels were assessed at baseline three months later. Results: Ninety-six patients with type 2 diabetes (74 women and 22 men) with the mean age of 55.7±9.9 years were studied. Significant reduction was seen in fasting blood sugar (FBS), 2 hours postprandial (2hpp) glucose, hemoglobin A1C and triglyceride levels three months after adding glutazone to therapeutic regimen (p< 0.0005). There was not a significant rise in cholesterol and HDL levels before and after the new therapy.Conclusion: The results show that the combination of glutazone, metformin and glibenclamide may result in better control of glycemic status in diabetic patients resistant to oral first-line agents. |
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| کلیدواژه‌های انگلیسی مقاله |
Type 2 Diabetes, Glutazone, Metformin, Glibenclamide |
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| نویسندگان مقاله |
ناصر آقامحمدزاده | naser aghamohammadzadeh
علی تبریزی | ali tabrizi
میترا نیافر | mitra niafar
فرزاد نجفی پور | farzad najafipor
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| نشانی اینترنتی |
http://www.caspjim.com/browse.php?a_code=A-10-62-3&slc_lang=en&sid=en |
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| کد مقاله (doi) |
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| زبان مقاله منتشر شده |
en |
| موضوعات مقاله منتشر شده |
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| نوع مقاله منتشر شده |
1 |
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